Ten people with type 1 diabetes (T1D), aged 28 to 57 years, attended an urban diabetes center for a retrospective observational study assessing the effects of intensive insulin treatment using continuous subcutaneous insulin infusion (insulin pump) and glucose monitoring systems. The study aimed to determine the impact of these interventions, including the hybrid insulin pump MiniMed 780G, on various clinical and laboratory parameters in T1D management. Participants had diabetes duration ranging from 8 months to 47 years, with some presenting with complications such as retinopathy, neuropathy, and nephropathy. The intervention involved long-term therapy with an insulin pump combined with either glucometer-strips systems or continuous glucose monitoring (CGM) sensors. The primary outcomes of interest were the changes in HbA1c levels, body mass, and insulin usage. Additionally, the study examined the effect of the hybrid insulin pump MiniMed 780G in 9 out of the 10 participants. Clinical and laboratory parameters were compared before and during the use of the hybrid insulin pump. The findings revealed a significant decrease in HbA1c levels by 8 (2-107) mmol/mol during the use of the hybrid insulin pump, indicating improved glycemic control. Changes in body mass and insulin usage were also evaluated, but no statistically significant differences were observed. In conclusion, this study supports the combination of adequate education, long-term therapy with an insulin pump, early implementation of CGM, and the use of the hybrid insulin pump MiniMed 780G as an optimal approach to T1D management. These interventions offer the potential for improved diabetes control and enhanced quality of life for individuals with T1D.

Noemi Novakova is a dedicated 5th-year medical student who is deeply passionate about the future of primary care and internal medicine. With a strong commitment to advancing medical knowledge and patient care, Noemi actively engages in student research and professional activities to contribute to the field. She actively participates in research projects, collaborating with fellow students and faculty members to explore the frontiers of medical science. Her work has been recognized and published in an open-access book under the title Benefits of Implementation of Insulin Pump in People with Type 1 Diabetes: 10 Case Reports. Noemi's research work has not only been acknowledged through publication but has also received high praise within her university.