
Farhana Faruque
Sir Salimullah Medical college, Mitford Hospital, BangladeshPresentation Title:
Association of Hypothyroidism with Type 2 Diabetes Mellitus: A Hospital based experience in a Tertiary Care Centre
Abstract
Thyroid diseases and diabetes
mellitus are the two most common endocrine disorders encountered in clinical
practice. Type 2 diabetes mellitus (T2DM) has an intersecting underlying
pathology with thyroid dysfunction. Insulin and thyroid hormones are intimately
involved in cellular metabolism and thus excess or deficit of either of these
hormones result in the functional derangement of the other. Despite the absence
of definite guidelines regarding screening for thyroid dysfunction in diabetic
patients, in the view of this incidence together with the mutual effect of the
common two endocrinopathies on each other and the increased risk of
complications in diabetic patients in the setting of abnormal thyroid
dysfunction, a systematic approach to thyroid testing in diabetic patients is
favorable.
Methods: A Cross sectional
descriptive observational study was performed at a tertiary care centre.
Patients of 30 years and older with known type 2 DM without thyroid disorders
between March 2018 to September 2018 were included in this study by purposive
sampling technique. A total of 100 patients were included in the study.
Results: Among the study patients, 13(26%) had thyroid abnormalities, 8 cases
were male, and 5 cases were female. Thyroid abnormality was associated with
duration of DM. The mean duration of disease was 6.28±2.57 years in patients
with normal thyroid profile group and 10.92±8.13 years in patients with
abnormal thyroid profile (hypothyroidism or hyperthyroidism) group. Patients
with poor glycemic control prone to develop endocrinopathies like thyroid
abnormality. HbA1c also shows the positive correlation with thyroid abnormality
in type 2 diabetes patients. Regarding the definition of thyroid abnormality,
7% patients had Primary hypothyroidism, 2% Subclinical hypothyroidism and 3%
primary hyperthyroidism and single case subclinical hyperthyroidism.
Conclusion: Our results demonstrate that hypothyroidism is the common thyroid
disorder in type 2 DM patient. It seems that unidentified thyroid dysfunction
could positively impact diabetes and its complications. The ability to diagnose
and treat unsuspected thyroid dysfunction in these patients may greatly enhance
the quality of life. Hence the need to detect such cases where thyroid
dysfunction contributes to morbidity and where it is the cause for poor control
of the associated conditions.
Biography
Farhana Faruque passed MBBS from Sir Salimullah Medical college,
Mitford Hospital in 2010. She has achieved FCPS in Internal Medicine from
Bangladesh College of Physician n Surgeon (BCPS) in 2021. Now she is serving
people of Bangladesh as a medicine consultant.