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Eva Maria Perusquia Frias

Salinas Valley Health Clinic, Mexico

Presentation Title:

Epigenetics and obesity

Abstract

Obesity is a chronic disease with multifactorial causes, treatable but until now not curable, with high cardiovascular impact and that cause a big social stigma. Obesity epidemic is developing worldwide, and it is not just a bad lifestyle or a lack of willingness. This problem is even worse in countries like the USA, México, and N. Zealand. 

Epigenetics is a science that study the changes in the expression and function of the genes by environmental factors without altering the DNA sequence, changing the phenotype and not the genotype, so that they are reversible but inherited. 

Factors like poor nutrition, hypoxia and  stress during pregnancy is well known have effects on offsprings, and these changes can be transmitted to subsequent generations as part of the fetal programming. 

Recently also has being studied the impact of paternal environmental factors linked to the development of obesity in offsprings, suggesting that poor paternal pre- conceptional nutrition and lifestyle can increase the risk of this disease.

Although evidence is mostly based on animal studies, the research on these factors to establish the link between environmental exposures and molecular changes that can be potentially reversible is not only necessary but urgent to design a more efficient strategy to prevent obesity since pregnancy, and we are committed to do everything we can to improve the chances of a healthier life.

Biography

Eva Perusquía is a physician graduated with  honors from La Salle University in México  City. She has a specialty in internal medicine from Hospital Español de México in México city with private clinical and hospital practice for 25 years. Also, she has a Master´s degree in Humanitarian Sciences by Universidad Anáhuac Querétaro and an MBA in Hospital and Health resources administration by Tech Universidad Tecnológica. For 12 years she was a mid- time professor at the medicine faculty of the Universidad Autónoma de Querétaro in  the physiology and nephrology courses. Former president of the Internal Medicine Board of Querétaro 2014 to 2017. Fellow of the American College of Physicians. Medical advisor for the neurosciences unit in México City 2022. Currently medical provider at Clínica de Salud del Valle de Salinas, California as part of the Pilot Mexican AB 1045 project. National and International lecturer in more than 70 seminars and meetings. Member of the Internal Medicine College of México and Sociedad Latinoamericana de Medicina Interna (SOLAMI)