Objective: The current study aimed to assess the impact of an educational program on the knowledge and attitude of caregivers toward the preventive measures of the sickle cell crisis. Methods: An interventional study was conducted in the Sickle Cell Outpatient Clinic of Gaafar Ibnauf Children's Specialized Hospital, Khartoum, Sudan. A simple random sampling of 286 caregivers of children with SCD who were on regular follow-up and attended the clinic during the study period was included. Data was collected using a pre-structured investigator-filled questionnaire. A paired samples test was used to assess the variance in the caregiver’s knowledge and attitude after implementing the educational program. Also, proportion and binomial tests were used to investigate the statistical significance of the variable of interest. Furthermore, a one-way analysis of variance (ANOVA) test was used to investigate the variance in caregivers’ knowledge and attitude toward the preventive measures of the sickle cell crisis related to their socio-demographic characteristics. The level of statistical significance used was < 0.05, and a 95% confidence interval was appropriate. The data were analyzed using the software package SPSS version 25. Results: The results of the current study revealed that the level of knowledge and attitude about the preventive measures of SCD crisis among caregivers was significantly higher after the implementation of the educational program. The percentage of caregivers with satisfactory knowledge and positive attitudes toward the preventive measures of the sickle cell crisis increased by 18% and 12%, respectively. The study indicated that the study group’s socio-demographic characteristics do not affect caregivers’ knowledge and attitude toward the preventive measures of sickle cell crisis (the P value was >0.05).

Fatma Abdalla is an assistant professor of pediatric nursing at Jazan University in KSA. She holds a Ph.D. in pediatric nursing from Al-Neelain University in Sudan. She held the position of Vice-dean for research and development for the College for 2 years and as head of the quality and academic accreditation unit for 3 years. She registered as a Nursing Specialist in the Saudi Commission for Health Specialties. She obtained the certificates, including academic quality practitioners, academic quality experts, and academic quality reviewers from OFUQ Academy, Malaysia, and the Learning Outcomes Specialist Certificate from Jazan University. She received a certificate of appreciation from the College of Nursing and Health Sciences for her contribution to completing the requirements for full academic accreditation of the nursing program. Fatma Abdalla is an academic researcher in nursing with a strong focus on women’s health, sickle cell disease, and caregiver-related research. Her scholarly work includes studies on breast cancer knowledge and attitudes, breast self-examination practices among women in Jazan, Saudi Arabia, and psychological health issues such as stress and anxiety symptoms among nursing students. She has also contributed to research on caregivers’ knowledge, attitudes, and health beliefs regarding sickle cell disease. In addition, she has published Perspective Chapters, such as Family Caregivers – Pioneering Pathways in Long-Term Care Innovation and Research, as well as Stem Cell Transplantation and Gene Therapy- Advances in the Management of Sickle Cell Disease. Her research interests span community health promotion and psychosocial aspects, with a strong emphasis on improving health awareness and patient outcomes in diverse populations.