Objective: The current study aimed to assess the impact of an educational program on the knowledge and attitude of caregivers toward the preventive measures of the sickle cell crisis. Methods: An interventional study was conducted in the Sickle Cell Outpatient Clinic of Gaafar Ibnauf Children's Specialized Hospital, Khartoum, Sudan. A simple random sampling of 286 caregivers of children with SCD who were on regular follow-up and attended the clinic during the study period was included. Data was collected using a pre-structured investigator-filled questionnaire. A paired samples test was used to assess the variance in the caregiver’s knowledge and attitude after implementing the educational program. Also, proportion and binomial tests were used to investigate the statistical significance of the variable of interest. Furthermore, a one-way analysis of variance (ANOVA) test was used to investigate the variance in caregivers’ knowledge and attitude toward the preventive measures of the sickle cell crisis related to their socio-demographic characteristics. The level of statistical significance used was < 0.05, and a 95% confidence interval was appropriate. The data were analyzed using the software package SPSS version 25. Results: The results of the current study revealed that the level of knowledge and attitude about the preventive measures of SCD crisis among caregivers was significantly higher after the implementation of the educational program. The percentage of caregivers with satisfactory knowledge and positive attitudes toward the preventive measures of the sickle cell crisis increased by 18% and 12%, respectively. The study indicated that the study group’s socio-demographic characteristics do not affect caregivers’ knowledge and attitude toward the preventive measures of sickle cell crisis (the P value was >0.05).

TBA